Journal of Nursing

Resting Regional Cerebral Perfusion in Drug-Free First-Episode Schizophrenia with Arterial Spin Labeling Magnetic Resonance Imaging

Bingqiang Xu, Xia Zhe


Objective This study aimed to explore the regional cerebral blood flow (rCBF) of first-episode schizophrenia (FES) by Arterial Spin Labeling (ASL) Magnetic Resonance Imaging (MRI) technique under resting condition. Method The rCBF was measured in 28 patients with FES and 28 healthy controls (HC). Result Patients with the FES showed significantly decreased rCBF. Conclusion Alteration of rCBF in FES patients observed in the current study suggested that the functional abnormalities of those areas were the features of early stage of the disease.


Arterial Spin Labeling; Magnetic Resonance Imaging; Regional Cerebral Blood Flow

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