Journal of Nursing

Research Progress of Survival Outcomes in Early-Stage Cervical Cancer Patients Undergoing Robotic Radical Hysterectomy

Xiaoxia Chang, Junying Tang


Minimally invasive surgical (MIS) for early-stage cervical cancer (ECC) has been controversial following the publication of The LACC trial. However, MIS consists of traditional laparoscopic surgery and robotic-assisted laparoscopic surgery. The aim of this article is to discuss the research progress of ECC undergoing robotic radical hysterectomy (RRH) with a view to providing more surgical options for patients.


Early-Stage Cervical Cancer; Robotic Radical Hysterectomy; Survival Outcomes

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Arbyn M, Weiderpass E, Bruni L, et al. Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Glob Health[J]. 2020 Feb;8(2):e191-e203.

NCCN Clinical Practice Guidelines in Oncology, Cervical Cancer.Version 2.2018.

Canis M, Mage G, Pouly J L, et al. Laparoscopic radical hysterectomy for cervical cancer[J]. Baillieres Clin Obstet Gynaecol. 1995 Dec;9(4):675-89.

Nezhat CR, Nezhat FR, Burrell MO, et al. Laparoscopic radical hysterectomy and laparoscopically assisted vaginal radical hysterectomy with pelvic and paraaortic node dissection[J]. J Gynecol Surg. 1993 Summer;9(2):105-20.

Wang YZ, Deng L, Xu HC, et al. Laparoscopy versus laparotomy for the management of early stage cervical cancer[J]. BMC Cancer. 2015 Nov 24;15:928.

Shah CA, Beck T, Liao JB, et al. Surgical and oncologic outcomes after robotic radical hysterectomy as compared to open radical hysterectomy in the treatment of early cervical cancer[J]. J Gynecol Oncol. 2017 Nov;28(6):e82.

Sert BM, Boggess JF, Ahmad S, et al. Robot-assisted versus open radical hysterectomy: A multi-institutional experience for early-stage cervical cancer[J]. Eur J Surg Oncol. 2016 Apr;42(4):513-22.

Mendivil AA, Rettenmaier MA, Abaid LN, et al. Survival rate comparisons amongst cervical cancer patients treated with an open, robotic-assisted or laparoscopic radical hysterectomy: A five year experience[J]. Surg Oncol. 2016 Mar;25(1):66-71.

Ramirez PT, Frumovitz M, Pareja R, et al. Minimally invasive versus abdominal radical hysterectomy for cervical cancer[J]. N Engl J Med. 2018;379(20):1895–904.

Bogani G, Cromi A, Uccella S, et al. Laparoscopic versus open abdominal management of cervical cancer: long-term results from a propensity-matched analysis[J]. J Minim Invasive Gynecol. 2014 Sep-Oct;21(5):857-62.

Wang W, Shang C, Huang J, et al. Long-term oncological outcomes after laparoscopic versus abdominal radical hysterectomy in stage I a2- II a2 cervical cancer: a matched cohort study[J]. Zhong hua Fu Chan Ke Za Zhi. 2015 Dec;50(12):894-901.

Chiva L, Zanagnolo V, Kucukmetin A, et al. SUCCOR study. An international european cohort observational study comparing minimally invasive surgery versus open abdominal radical hysterectomy in patients with stage IB1 (FIGO 2009,<4 cm) cervical cancer operated in 2013–2014[J]. Int J Gynecol Cancer.2019:29:A1–2.

Sert BM, Abeler VM. Robotic-assisted laparoscopic radical hysterectomy with node dissection-case report[J].Eur J Gynaecol Oncol,2006: 531-533.

Zanagnolo V, Baroni C, Achilarre MT, et al. Oncological outcomes of robotic radical hysterectomy (RRH) for patients with early stage cervical cancer: experience at a referral cancer center[J]. Ann Surg Oncol. 2020.

Alfonzo E, Wallin E, Ekdahl L, et al. No survival difference between robotic and open radical hysterectomy for women with early-stage cervical cancer: results from a nationwide population based cohort study[J]. Eur J Cancer. 2019;116:169–77.

Jensen PT, Schnack TH, Froding LP, et al. Survival after a nationwide adoption of robotic minimally invasive surgery for early-stage cervical cancer -a population-based study[J]. Eur J Canc 2020;128:47e56.

Falconer H, Palsdottir K, Stalberg K, et al. Robot-assisted approach to cervical cancer (RACC): an international multi-center,open-label randomized controlled trial[J]. Int J Gynecol Cancer.2019;29(6):1072–6.

Shazly SA, Murad MH, Dowdy SC, et al. Robotic radical hysterectomy in early stage cervical cancer: a systematic review and meta-analysis. Gynecol Oncol 2015; 138: 457–71.

Walker JL, Piedmonte MR, Spirtos NM, et al. Recurrence and survival after random assignment to laparoscopy versus laparotomy for comprehensive surgical staging of uterine cancer: Gynecologic Oncology Group LAP2 Study[J]. J Clin Oncol. 2012 Mar 1;30(7):695-700.

Kearney DE, Coffey JC. A Randomized Trial of Laparoscopic versus Open Surgery for Rectal Cancer[J]. N Engl J Med. 2015 Jul 9;373(2):194.

Choi CH, Lee JW, Lee YY, et al. Comparison of laparoscopic-assisted radical vaginal hysterectomy and laparoscopic radical hysterectomy in the treatment of cervical cancer[J]. Ann Surg Oncol. 2012 Nov;19(12):3839-48.

Passerotti CC, Franco F, Bissoli JC, et al. Comparison of the learning curves and frustration level in performing laparoscopic and robotic training skills by experts and novices[J]. Int Urol Nephrol. 2015 Jul;47(7):1075-84.

Ponce J, Fernandez-Gonzalez S, Gil-Moreno A, et al. Risk Factors for Recurrence after Robot-Assisted Radical Hysterectomy for Early-Stage Cervical Cancer: A Multicenter Retrospective Study[J]. Cancers (Basel). 2020 Nov 16;12(11):3387.

Shah CA, Beck T, Liao JB, et al. Surgical and oncologic outcomes after robotic radical hysterectomy as compared to open radical hysterectomy in the treatment of early cervical cancer[J]. J Gynecol Oncol. 2017 Nov;28(6):e82.



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