The Progress of Aptamers in the Detection of SARS-CoV-2
Abstract
SARS-CoV-2 has caused millions of deaths worldwide since its outbreak and will continue to cause large-scale global infections, so it is of great significance for the prevention and control of diseases caused by this virus to develop rapid and portable detection methods. Currently, PCR detection of SARS-CoV-2 is generally time-consuming and complicated, while aptamers, as a new type of biorecognition that can specifically recognize small molecules such as proteins, nucleic acids, oligonucleotides, etc., have a great potential and advantage in the detection of SARS-CoV-2. This review briefly describes the detection principle, characteristics and specific applications of aptamers combined with biosensor technology in the detection of SARS-CoV-2, and discusses the advantages, challenges and future development tendency in the area of SARS-CoV-2 detection.
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DOI: http://dx.doi.org/10.18686/jn.v12i3.290
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