Efficacy of Low Molecular Weight Heparin Versus Low-Dose Aspirin in the Treatment of Recurrent Miscarriage in Prethrombotic States

Abstract

Objective: To explore the application effect of low-molecular-weight heparin and low-dose aspirin in the treatment of recurrent abortion with pre thrombotic state. Method: 80 patients with recurrent miscarriage and prethrombotic state admitted to our hospital from February 2022 to February 2023 were selected as the study subjects. They were randomly divided into a control group and an observation group of 40 cases each. The control group received low-molecular-weight heparin treatment, while the observation group received a combination of low-molecular-weight heparin and low-dose aspirin for treatment. Compare the outcomes of two groups after completing different treatments. Results: By observing the thrombin time, D-dimer index and pregnancy outcome of the two groups, the thrombin time and pregnancy outcome of the observation group were significantly higher than those of the control group, while the D-dimer index of the observation group was significantly lower than that of the control group, with statistically significant differences (P<0.05). Conclusion: The application of low-molecular-weight heparin and low-dose aspirin in the treatment of prethrombotic state of recurrent abortion can effectively improve the outcome of pregnancy, reduce the D-dimer index of patients, and optimize the thrombin time of patients. It has high clinical application value and is worth promoting.