Mechanisms of Action and Formulation Development of Skin-Whitening Cosmetics
Abstract
Skin-whitening cosmetics are widely used in cosmetic dermatology to address issues related to uneven skin tone and pigmentation.
This paper provides a comprehensive analysis of the mechanisms of action of skin-whitening ingredients and explores their applications in
skincare. The inhibition of melanin synthesis, promotion of melanin metabolism, and blockade of tyrosinase activity are key factors in the
mechanism of action. Effective inhibitors, such as salicylic acid and arbutin, have been developed to target tyrosinase and slow down melanin
formation. Additionally, antioxidant ingredients like vitamin C and E are used to neutralize free radicals and enhance the skin’s antioxidant
capacity, thereby promoting the whitening effect. In terms of formulation development, this paper considers ingredient compatibility, permeability, and stability to ensure the efficacy and safety of skin-whitening cosmetics.
This paper provides a comprehensive analysis of the mechanisms of action of skin-whitening ingredients and explores their applications in
skincare. The inhibition of melanin synthesis, promotion of melanin metabolism, and blockade of tyrosinase activity are key factors in the
mechanism of action. Effective inhibitors, such as salicylic acid and arbutin, have been developed to target tyrosinase and slow down melanin
formation. Additionally, antioxidant ingredients like vitamin C and E are used to neutralize free radicals and enhance the skin’s antioxidant
capacity, thereby promoting the whitening effect. In terms of formulation development, this paper considers ingredient compatibility, permeability, and stability to ensure the efficacy and safety of skin-whitening cosmetics.
Keywords
Skin-Whitening Cosmetics; Mechanisms of Action; Formulation Development
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DOI: http://dx.doi.org/10.18686/nursing.v12i4.314
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