Journal of Nursing

Study of Safe Medication Use and Nursing Guidance for Elderly Patients with Coexisting Chronic Diseases

Ping Shu, Hengying Che, Wenqian Hong, Wenjing Liu, Wenjing Chen


Objective: This study aims to explore the efficacy of implementing pharmacotherapy guidance in the context of safe medication
practices for elderly patients with comorbid chronic illnesses. Eighty cases of elderly patients with coexisting chronic diseases admitted to
our hospital between May 2023 and December 2023 were selected and grouped according to the randomized numerical table method, with
conventional nursing care implemented in the control group (n=40) and safe medication nursing guidance implemented in the observation
group (n=40), to compare the quality of life scores of the patients in both groups before and after nursing care; the safety of the medication;
the medication adherence scores before and after nursing care; the nursing somatic function before and after nursing. Results: Before nursing care, the quality of life scores of patients in the two groups were compared (P > 0.05), and after nursing care, the quality of life scores of
patients in the observation group were higher than those of patients in the control group (P < 0.05); The rate of unauthorized drug increase,
unauthorized drug decrease, drug omission rate and unauthorized drug discontinuation rate of patients in the observation group were lower
than those of patients in the control group, and the difference was statistically significant (P < 0.05); before nursing, the medication adherence
scores of the two groups were compared (P > 0.05), and after nursing, the medication adherence scores of the observation group were higher
than those of the control group (P < 0.05); before nursing, the comparison of the somatic function of the two groups was compared (P > 0.05).
After nursing care, the 6min walking distance, grip strength, and MMSE scores of patients in the observation group were higher than those of
patients in the control group, and the 10m walking time of patients in the observation group was less than that of patients in the control group (P
< 0.05). Conclusion: Elderly patients with coexisting chronic diseases can further improve their medication adherence, safety, quality of life,
and somatic function through safe medication nursing guidance intervention, which is worth promoting


Chronic Illness in the Elderly; Safe Medication Use; Nursing Interventions; Nursing Outcomes

Full Text:


Included Database


[1] Manuel JH, Iria D, Cayetano F, et al. Spanish version of the Self-Care of Chronic Illness Inventory: A validation study amongst

community-dwelling older adults with chronic multimorbidity[J].Journal of advanced nursing,2023(1):22-30.

[2] Thomas B, Brigitte G. Maintaining autonomy: How older persons with chronic conditions and their significant others interpret,

navigate, and overcome everyday difficulties.[J].Scandinavian journal of occupational therapy,2023,31(1):11-15.

[3] Mendes SK, Rino AV, Fitrya ME, et al.Effectiveness of Otago Exercise on Health Status and Risk of Fall Among Elderly with

Chronic Illness[J].Jurnal Keperawatan Indonesia, 2020, 23(1): 15-22.

[4] Esmee V, W A C B, M H R G D, et al. The effect of Active Plus, a computer-tailored physical activity intervention, on

cognitive functioning of elderly people with chronic illness(es) - study protocol for a randomized controlled trial.[J].BMC public


[5] Katarzyna P, Magdalena S. Perceptions of Own Illness among the Elderly as Measured by the Brief-IPQ Scale and the IPIS[J]. International Journal of Environmental Research and Public Health, 2022, 19(8):4665-4669.

[6] Naga S, Shulamite PS, Suvashisa R, et al.Impact of positive health resources on psychological distress in elderly with chronic

illness: Revelations from latent profile analysis[J].Indian Journal of Gerontology,2022,36(1):45-67.

[7] CheeTao C, JuYing A, Asiful MI, et al. Prevalence of Drug-Related Problems and Complementary and Alternative Medicine Use

in Malaysia: A Systematic Review and Meta-Analysis of 37,249 Older Adults[J]. Pharmaceuticals,2021,14(3):187-191.

[8] J N A, N S H, Lisa K, et al. COVID-19 Pandemic: Considerations for Safe Medication Use in Older Adults with Multimorbidity

and Polypharmacy.[J].The journals of gerontology. Series A, Biological sciences and medical sciences,2020,76(6):1068-1073.

[9] Zhongxun H, Javaid FS, Qiao F, et al.Trends of chronic illness in emergency department admissions among elderly adults in a tertiary hospital over ten years[J].BMC Health Services Research,2021,21(1):1305-1305.

[10]Savithri P, Priya V, Princy P, et al. A study of medication compliance in geriatric patients with chronic illness[J].Journal of Family

Medicine and Primary Care,2021,10(4):1644-1648.

[11]Faronbi OJ, Faronbi OG, Ayamolowo JS, et al.Caring for the seniors with chronicillness: The lived experience of caregivers of

older adults[J].Archives of Gerontology and Geriatrics, 2019, 828-832.

[12]In GS, Yean HP. The Effects of Self-Management Program and Its Measurement for the Elderly with Chronic Illness in the com_x0002_munity[J]. Korea Gerontological Society, 2020, 40(2): 257-267.

[13]C. MZ, Klodiana M, Michelle N, et al.Optimizing Older Adults’ Medication Use Nurses can partner with caregivers to promote

safe medication administration.[J].Home Healthcare Now,2022,40(6):304-310.

[14]Nicole K, Annatjie B, Renier C. Pharmacists’ Approach to Optimise Safe Medication Use in Paediatric Patients.[J].Pharmacy (Basel,


[15]Shin YJ, Noh Y, Park JB. Safe Medication Use for Guaranteeing Patient Safety[J].Yakhak Hoeji, 2020,64(3):185-190.

[16]Borgsteede DS. Recommendations for Safe Medication Use in Liver Impairment: Importance of Transparency and Reflections on

Analgesics, Hypnotics, and Anti-emetics[J].Journal of Pain and Symptom Management,2020,59(3):e6-e8.

[17]Raj BED, Kanniammal. A study to assess the effectiveness of selected nursing intervention on activities of daily living, self esteem,

depression and quality of life among elderly with chronic illness at selected old age homes in Bangalore, Karnataka[J].International Journal

of Psychiatric Nursing,2018,4(2):113-118.

[18]V. VP, Rekha U. Psychosocial problems, chronic illness and welfare service utilization among elderly population in urban areas of

Vijayapur, Karnataka[J].International Journal Of Community Medicine And Public Health,2018,5(8):3383-3388.

[19]Della M, Lucie R, Michelle D, et al.Negotiating health and chronic illness in Filipino-Australians: a qualitative study with implications for health promotion.[J].Ethnicity health,2018,23(6):611-628.

[20]Purnama WPNS, Jintana A. Comparison of Attitudes Towards Meditation Healing Exercise between the Elderly Living with

Chronic Illness in Bangkok and Surabaya[J]. Jurnal Ners, 2018, 13(1): 57-59.



  • There are currently no refbacks.

Copyright (c) 2024 Ping Shu,Hengying Che,Wenqian Hong,Wenjing Liu,Wenjing Chen