Journal of Nursing

Advances in biomarker and score combinations for predicting sepsis disease and prognosis

Min Zhang, JiaJia Du, GaoYing Li, HanYu Lei, ChunYan Zhao*

Abstract


Sepsis-related research has progressed considerably with more than 250 biomarkers have been identified in the field, but none of
the tests are sensitive or specific enough to diagnose sepsis alone. The ideal biomarker for the diagnosis and prognostic stratification of patients with sepsis remains unidentified. The combination of clinical scores and biomarkers can improve diagnostic and prognostic accuracy
in sepsis, so finding the ideal combination is critical. The aim of this review is to sort out the different combinations of sepsis biomarkers and
clinical scores in the current literature in order to find the ideal combination that can effectively predict the condition and prognosis, and provide a scientific reference to reduce the mortality of patients with enhanced quality of survival and improved clinical management outcomes.

Keywords


Sepsis; Biomarkers; Score

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References


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DOI: http://dx.doi.org/10.18686/nursing.v13i4.368

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